Palmar Hyperhidrosis Treatment: An Overview

Palmar hyperhidrosis, commonly referred to as excessive hand sweating, can often be a source of discomfort and embarrassment for many individuals. This condition can pose various problems such as difficulty in handling papers, leaving damp handprints on significant surfaces, and causing social anxiety. Although it is a benign condition, it can have a profound impact on the quality of life. Thus, the treatment for palmar hyperhidrosis is essential to increase the individual’s comfort and alleviate the accompanying psychological distress.

There are various treatment options currently available for palmar hyperhidrosis which have proven effective in managing the condition. This article will explore these various treatment options, to help those suffering from this condition find an appropriate treatment plan.

Topical Treatments

One of the first-line treatments for palmar hyperhidrosis is the use of topical treatments, which are directly applied to the skin surface. These include antiperspirants containing aluminum chloride, creams, lotions, and other topical formulations. Topical treatments work by blocking the sweat ducts, reducing the amount of sweat that reaches the skin surface. While this is an affordable and non-invasive approach, it often requires regular application, and may not be effective in severe cases of palmar hyperhidrosis.

Oral Medications

Oral medications, known as anticholinergics, can also be used in the treatment of palmar hyperhidrosis. These drugs work by disrupting the communication between the nerves and sweat glands, thus reducing the production of sweat. However, these drugs can have side effects such as dry mouth, constipation, and blurred vision. Therefore, the benefits and risks should be thoroughly discussed with a healthcare professional.


Iontophoresis is a non-invasive procedure that can be pursued for the treatment of palmar hyperhidrosis. During iontophoresis, a medical device is used to pass a mild electrical current through water and into the skin’s surface. This disrupts the function of the sweat glands temporarily. Multiple sessions may be required for the desired effect, although the results can last for several weeks. It’s advisable to use this treatment option under the guidance of a healthcare provider.

Botulinum Toxin Injections (Botox)

Botox is a drug made from a neurotoxin produced by the bacterium Clostridium botulinum. Botox works by blocking the nerves responsible for activating the sweat glands. This treatment is reliable and can provide relief from sweating for several months. However, the injections can be painful, and the treatment needs to be repeated every few months.

Surgical Treatment

In severe cases of palmar hyperhidrosis where other treatment options have failed, surgical intervention may be considered. This can involve a procedure known as endoscopic thoracic sympathectomy (ETS), where the nerves that control sweating are cut or clamped. This treatment is permanent but does come with the risk of compensatory sweating in other parts of the body.

In conclusion, palmar hyperhidrosis is a treatable medical condition with multiple options available. It is important to seek advice from a healthcare professional to discuss the most suitable treatment method for your situation. You can find more comprehensible and in-depth information on this topic on the Sweaty Palms site.